Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305380 | 0.93 | AKR1A1 (0.55) | AKR1A1AKR1B1 | |
| SCHEMBL8308531 | 0.89 | AKR1A1 (0.48) | AKR1A1AKR1B1 | |
| SCHEMBL8308463 | 0.89 | AKR1A1 (0.55) | AKR1A1AKR1B1 | |
| SCHEMBL8307547 | 0.88 | AKR1B1 (0.53) | AKR1A1AKR1B1 | |
| SCHEMBL8307226 | 0.85 | AKR1A1 (0.54) | AKR1A1AKR1B1 | |
| SCHEMBL8307950 | 0.83 | AKR1B1 (0.55) | AKR1A1AKR1B1 | |
| SCHEMBL8304777 | 0.83 | AKR1B1 (0.45) | AKR1A1AKR1B1 | |
| SCHEMBL8307973 | 0.82 | AKR1B1 (0.52) | AKR1A1AKR1B1 | |
| SCHEMBL8305325 | 0.79 | AKR1A1 (0.47) | AKR1A1AKR1B1 | |
| SCHEMBL8307246 | 0.77 | AKR1B1 (0.54) | AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633261-B1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | YOSHITOMI PHARMACEUTICAL (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5543420-A | ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AGENTS; PREVENTION OF ACCUMULATION OF SORBITOL AND GALACTITOL IN MAMMALIAN TISSUE | THE GREEN CROSS CORPORATION (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0633261-A1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1995-01-11 | — | — | EP | disclosed |