Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578901 | 0.86 | GAA (0.42) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6577096 | 0.83 | GAA (0.44) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL3735228 | 0.82 | KMT2A (0.49) | ALDH1A1ALOX12KMT2AKDM4EHSD17B10 | |
| SCHEMBL6579987 | 0.81 | GAA (0.49) | GAAALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6579489 | 0.81 | GAA (0.51) | GAAALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6579314 | 0.77 | ALDH1A1 (0.44) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6582955 | 0.77 | ALDH1A1 (0.44) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6581936 | 0.76 | ALDH1A1 (0.49) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10364413 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPTALOX12KMT2AKDM4E | |
| SCHEMBL3735946 | 0.74 | KMT2A (0.46) | ALDH1A1ALOX12KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |