Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | BACE1 | P56817 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312032 | 0.99 | TP53 (0.63) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8312492 | 0.99 | TP53 (0.63) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8306905 | 0.92 | KDM4E (0.65) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8312639 | 0.91 | TP53 (0.64) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8308219 | 0.91 | KDM4E (0.72) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8309383 | 0.90 | TP53 (0.66) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8311992 | 0.89 | KDM4E (0.58) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8305989 | 0.86 | MEN1 (0.68) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8311670 | 0.86 | TP53 (0.57) | TP53BACE1HTTALDH1A1LMNA | |
| SCHEMBL8307719 | 0.86 | POLB (0.58) | TP53BACE1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |