SCHEMBL830895

SCHEMBL830895

CC1=Cc2c(cccc2-n2c3ccccc3c3ccccc32)C1[Si](C)(C)C1C(C)=Cc2c1cccc2-n1c2ccccc2c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
DUSP3 P51452 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
FTO Q9C0B1 1/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3759072 1.00 ALDH1A1 (0.35) ALDH1A1L3MBTL1KDM4EATMPOLB
SCHEMBL16393769 0.82 PDK2 (0.32)
Hydrochloric Acid SCHEMBL18187045 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL30472805 0.79 ALDH1A1 (0.39) ALDH1A1L3MBTL1KDM4EATMPOLB
Hydrochloric Acid SCHEMBL3690620 0.79 ALDH1A1 (0.36) ALDH1A1L3MBTL1KDM4EATMPOLB
SCHEMBL31253546 0.79 ALDH1A1 (0.39) ALDH1A1L3MBTL1KDM4EATMPOLB
SCHEMBL19813085 0.78 ALDH1A1 (0.35) ALDH1A1L3MBTL1KDM4EATMALKBH5
SCHEMBL3743352 0.77 BIRC5 (0.33)
SCHEMBL3690622 0.77 ALDH1A1 (0.34) ALDH1A1L3MBTL1KDM4EATM
SCHEMBL3751290 0.77 CYP1A2 (0.35) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240520-B1 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-04-24 EP disclosed
US-8455589-B2 Polymerization process and adhesives therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-06-04 US disclosed
US-20120149829-A1 Polymerization Process And Adhesives Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2012-06-14 US disclosed
US-8143353-B2 Polymerization process and adhesives therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-03-27 US disclosed
EP-2240520-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS ExxonMobil Chemical Patents Inc. (US) 2010-10-20 EP disclosed
US-7812104-B2 Production of propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-10-12 US disclosed
US-20090239999-A1 Polymerization Process and Adhesives Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2009-09-24 US disclosed
EP-2103634-A1 Production of propylene-based polymers ExxonMobil Chemical Patents Inc. (US) 2009-09-23 EP disclosed
US-20090186995-A1 Production of Propylene-Based Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2009-07-23 US disclosed
WO-2009091480-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-07-23 WO disclosed