Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.52 |
| ▸ | MAOA | P21397 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CALML3 | P27482 | 1/20 | 0.46 |
| ▸ | SDHA | P31040 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898022 | 0.86 | MAOB (0.56) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8447305 | 0.85 | CALML3 (0.57) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8310783 | 0.84 | MAOB (0.52) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8308178 | 0.84 | MAOB (0.52) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL12126884 | 0.84 | MAOB (0.72) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL14982833 | 0.84 | MAOB (0.72) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL13314692 | 0.84 | MAOB (0.59) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8447994 | 0.83 | MAOB (0.54) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8450711 | 0.83 | MAOB (0.54) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7485004 | 0.82 | MAOB (0.57) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918770-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | AstraZeneca AB (SE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998001447-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ZENECA LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |