Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 5/20 | 0.57 |
| ▸ | MAOB | P27338 | 11/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SDHA | P31040 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12527857 | 0.88 | CALML3 (0.51) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8575816 | 0.86 | MAOA (0.71) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8575809 | 0.86 | MAOA (0.71) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14345224 | 0.86 | MAOB (0.61) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL28428084 | 0.86 | MAOB (0.58) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL28110345 | 0.86 | MAOB (0.58) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL12525561 | 0.85 | MAOA (0.57) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8308966 | 0.85 | MAOB (0.52) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8310567 | 0.83 | CALML3 (0.60) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14898018 | 0.83 | CALML3 (0.61) | CALML3MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918770-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | AstraZeneca AB (SE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998001447-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ZENECA LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |