Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305997 | 0.90 | MAOB (0.64) | MAOBMAOAABCB1PPARGALDH1A1 | |
| SCHEMBL4575969 | 0.86 | MAOB (0.54) | MAOBMAOAABCB1PPARGALDH1A1 | |
| SCHEMBL8305728 | 0.81 | MAOB (0.66) | MAOBMAOAABCB1ALDH1A1CYP3A4 | |
| SCHEMBL8431040 | 0.81 | HPGD (0.62) | MAOBMAOAABCB1PPARGALDH1A1 | |
| SCHEMBL17185518 | 0.81 | ABCB1 (0.69) | MAOBMAOAABCB1ALDH1A1KDM4E | |
| SCHEMBL8309183 | 0.80 | MAOB (0.51) | MAOBMAOAABCB1PPARGALDH1A1 | |
| SCHEMBL8304510 | 0.79 | MAOB (0.57) | MAOBMAOAABCB1ALDH1A1KDM4E | |
| SCHEMBL8431289 | 0.77 | ABCB1 (0.50) | MAOBMAOAABCB1PPARGALDH1A1 | |
| SCHEMBL8309779 | 0.76 | ABCB1 (0.56) | MAOBMAOAABCB1ALDH1A1KDM4E | |
| SCHEMBL4575095 | 0.76 | CYP1B1 (0.58) | MAOBMAOAABCB1PLGFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | claimed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | claimed |