Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305997 | 0.87 | MAOB (0.64) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL8304506 | 0.84 | MEN1 (0.57) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL8305728 | 0.82 | MAOB (0.66) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL8309007 | 0.79 | MAOB (0.53) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL8309183 | 0.77 | MAOB (0.51) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL8431040 | 0.77 | HPGD (0.62) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL17193738 | 0.76 | MAOB (0.82) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL19354052 | 0.74 | FLT3 (0.67) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL19129504 | 0.72 | MAOB (0.79) | MAOBMAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL20275158 | 0.71 | MAPT (0.72) | MAOBMAOAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |