Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 13/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.38 |
| ▸ | AKT1 | P31749 | 6/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 5/20 | 0.38 |
| ▸ | AURKA | O14965 | 8/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3000659 | 0.91 | RPS6KB1 (0.42) | RPS6KB1AURKBAKT1INCENPAURKA | |
| Hydrochloric Acid SCHEMBL6327132 | 0.90 | RPS6KB1 (0.42) | RPS6KB1AURKBAKT1INCENPAURKA | |
| SCHEMBL2998315 | 0.82 | F10 (0.40) | RPS6KB1AURKBAKT1INCENPAURKA | |
| SCHEMBL6326555 | 0.79 | F10 (0.36) | RPS6KB1AURKBAKT1INCENPAURKA | |
| SCHEMBL8304367 | 0.78 | F10 (0.46) | RPS6KB1AURKBAKT1INCENPAURKA | |
| Hydrochloric Acid SCHEMBL6332068 | 0.77 | F10 (0.46) | RPS6KB1AURKBAKT1INCENPAURKA | |
| SCHEMBL6323108 | 0.76 | CDK1 (0.44) | RPS6KB1AURKBAKT1INCENPAURKA | |
| SCHEMBL6324252 | 0.70 | F10 (0.44) | RPS6KB1AURKBAKT1INCENPAURKA | |
| SCHEMBL6322214 | 0.70 | CDK1 (0.39) | CNR1CNR2EGFRCDK1 | |
| SCHEMBL2996587 | 0.68 | CNR1 (0.37) | RPS6KB1AURKBAKT1INCENPAKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080970-A1 | NOVEL BICYCLIC AROMATIC COMPOUNDS, THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-23 | — | — | WO | disclosed |