Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14571577 | 1.00 | HTR1A (0.41) | HTR1AKMT2AMEN1CCR1DRD4 | |
| SCHEMBL14571583 | 1.00 | HTR1A (0.41) | HTR1AKMT2AMEN1CCR1DRD4 | |
| Hydrochloric Acid SCHEMBL5584294 | 0.99 | HTR1A (0.41) | HTR1AKMT2AMEN1CCR1DRD4 | |
| Hydrochloric Acid SCHEMBL5585058 | 0.99 | HTR1A (0.41) | HTR1AKMT2AMEN1CCR1DRD4 | |
| SCHEMBL14571540 | 0.91 | CCR1 (0.44) | HTR1AKMT2AMEN1CCR1DRD4 | |
| SCHEMBL6809839 | 0.91 | MEN1 (0.42) | HTR1AKMT2AMEN1CCR1DRD4 | |
| SCHEMBL14571581 | 0.90 | HTR1A (0.46) | HTR1ADRD4DRD2SLC6A4 | |
| Bromide SCHEMBL5585014 | 0.90 | MEN1 (0.41) | HTR1AKMT2AMEN1CCR1DRD4 | |
| SCHEMBL14571587 | 0.90 | HTR1A (0.42) | HTR1AKMT2AMEN1CCR1DRD4 | |
| SCHEMBL14571601 | 0.90 | HTR1A (0.41) | HTR1AKMT2AMEN1CCR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082686-A2 | USE OF COMPOUNDS WITH COMBINED 5-HT1A AND SSRI ACTIVITIES TO TREAT SEXUAL DYSFUNCTION | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |