Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309517 | 0.90 | TBXAS1 (0.66) | TBXAS1TBXA2R | |
| SCHEMBL8308715 | 0.88 | TBXAS1 (0.55) | TBXAS1TBXA2R | |
| SCHEMBL8306419 | 0.83 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8308584 | 0.79 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL8308553 | 0.79 | TBXAS1 (0.51) | TBXAS1 | |
| SCHEMBL14327858 | 0.79 | TBXA2R (1.00) | TBXAS1TBXA2R | |
| SCHEMBL27316638 | 0.79 | TBXAS1 (0.77) | TBXAS1TBXA2R | |
| SCHEMBL8595578 | 0.79 | TBXAS1 (0.77) | TBXAS1TBXA2R | |
| SCHEMBL9130164 | 0.78 | TBXA2R (0.81) | TBXAS1TBXA2R | |
| SCHEMBL8595627 | 0.76 | TBXAS1 (0.73) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579618-B1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1999-10-13 | — | — | EP | disclosed |
| US-5457118-A | Pyridine derived agents for cardiovascular diseases | PFIZER INC. (US) | 1995-10-10 | — | — | US | disclosed |