Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82940 | 0.85 | TSHR (0.48) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| SCHEMBL151981 | 0.84 | TSHR (0.65) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| SCHEMBL11670749 | 0.81 | TSHR (0.61) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL31241190 | 0.81 | TSHR (0.61) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL15864874 | 0.81 | TSHR (0.61) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| SCHEMBL28193891 | 0.81 | TSHR (0.61) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| SCHEMBL10839861 | 0.79 | KCNN4 (0.39) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| SCHEMBL2834337 | 0.79 | KCNN4 (0.39) | TSHRCYP1A2KCNN4ALDH1A1MAPK1 | |
| SCHEMBL2164357 | 0.75 | ESR1 (0.54) | TSHRKCNN4ALDH1A1MAPK1TAAR1 | |
| SCHEMBL294517 | 0.75 | ESR1 (0.54) | TSHRKCNN4ALDH1A1MAPK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |
| US-4046656-A | Photochlorination process for methyl aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1977-09-06 | — | — | US | disclosed |