SCHEMBL151981

SCHEMBL151981

ClC(Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
CYP1A2 P05177 2/20 0.50
KCNN4 O15554 4/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPK1 P28482 1/20 0.41
TAAR1 Q96RJ0 1/20 0.38
ALOX15 P16050 1/20 0.38
BBOX1 O75936 1/20 0.37
EHMT2 Q96KQ7 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
PTPN1 P18031 1/20 0.36
ESR1 P03372 1/20 0.36
CYP3A4 P08684 1/20 0.36
ESR2 Q92731 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL31241190 0.97 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1MAPK1
SCHEMBL11670749 0.97 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1MAPK1
SCHEMBL28193891 0.97 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL15864874 0.97 TSHR (0.61) TSHRCYP1A2KCNN4ALDH1A1MAPK1
SCHEMBL7649802 0.86 KIF11 (0.54) TSHRCYP1A2KCNN4ALDH1A1MAPK1
SCHEMBL7646185 0.86 TSHR (0.50) TSHRCYP1A2MAPK1
SCHEMBL11724522 0.84 TSHR (0.55) TSHRCYP1A2KCNN4ALDH1A1MAPK1
SCHEMBL7644095 0.84 TSHR (0.48) TSHRCYP1A2ALDH1A1MAPK1ESR1
SCHEMBL2363291 0.84 TSHR (0.48) TSHRCYP1A2KCNN4ALDH1A1MAPK1
SCHEMBL4462107 0.84 KCNN4 (0.50) TSHRCYP1A2KCNN4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118015-A Non-surafaxin intermediate and preparation method thereof 上海药坦药物研究开发有限公司 2025-06-10 CN claimed
CN-119954769-A Lipoic acid derived ceramide and synthesis method and application thereof 深圳市迪克曼生物科技有限公司 2025-05-09 CN claimed
CN-116396344-B Application of natural flavonoid glycoside in preparation of drugs for treating glycolipid metabolism comprehensive disturbance 江苏灵源沂岸科技股份有限公司 2025-04-29 CN claimed
CN-119798051-A Entecavir intermediate Process for the preparation of intermediates 江西贝美药业有限公司 2025-04-11 CN claimed
CN-119751376-A Preparation method of thifluzamide 广东禾康精细化工有限公司 2025-04-04 CN claimed
CN-115975162-B Di-o-chlorodiphenylamine methane modified castor oil polyol and preparation method thereof 江苏三木化工股份有限公司 2025-03-04 CN claimed
CN-119463291-A Method for upgrading, recovering and preparing multicolor fluorescent polymer material by using acrylic polymers 福建师范大学 2025-02-18 CN claimed
CN-119369599-A Manufacturing process and equipment of diaphragm, diaphragm and filter press 杭州安永环保科技有限公司 2025-01-28 CN claimed
CN-118994148-A Preparation method and intermediate of non-neridrone 奥锐特药业股份有限公司 2024-11-22 CN claimed
CN-118420542-B Preparation method of enzae Lu An 奥锐特药业股份有限公司 2024-11-12 CN claimed
US-5015710-A Catalytic addition polymerization HERCULES INCORPORATED (US) 1991-05-14 US claimed
EP-0423521-A1 Process for producing polymer molded article HERCULES INCORPORATED (US) 1991-04-24 EP claimed
EP-0376198-A2 Phosphorus compounds that delay the metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1990-07-04 EP claimed
US-4933402-A Phosphorus compounds that delay the metathesis polymerization of cycloolefins HERCULES INCORPORATED (US) 1990-06-12 US claimed
US-4883849-A SECONDARY OR TERTIARY AMINES, REACTION INJECTION MOLDING HERCULES INCORPORATED (US) 1989-11-28 US claimed
EP-0132866-A1 Alpha-halogenated aromatic compounds as photoinitiators STAUFFER CHEMICAL COMPANY (US) 1985-02-13 EP claimed
US-4380554-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1983-04-19 US claimed
EP-0044595-A1 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-27 EP claimed
US-4310657-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1982-01-12 US claimed
US-4013817-A HALOGENATED AROMATIC HYDROCARBON BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-03-22 US claimed