Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.70 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.60 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312674 | 0.92 | EGLN1 (0.59) | EGLN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL7691128 | 0.83 | EGLN1 (0.66) | EGLN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL7689791 | 0.83 | EGLN1 (0.69) | EGLN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL2200760 | 0.83 | EGLN1 (1.00) | EGLN1ALDH1A1 | |
| SCHEMBL8309666 | 0.81 | EGLN1 (0.63) | EGLN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL8310038 | 0.81 | EGLN1 (1.00) | EGLN1ALDH1A1 | |
| SCHEMBL7690131 | 0.80 | EGLN1 (0.65) | EGLN1PRMT5WDR77ALDH1A1 | |
| SCHEMBL7954435 | 0.79 | EGLN1 (0.63) | EGLN1ALDH1A1 | |
| SCHEMBL7954438 | 0.79 | EGLN1 (0.63) | EGLN1ALDH1A1 | |
| SCHEMBL2292957 | 0.79 | EGLN1 (0.86) | EGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | claimed |