Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.52 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.52 |
| ▸ | PRKACA | P17612 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PRKX | P51817 | 2/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.52 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954438 | 1.00 | EGLN1 (0.63) | EGLN1ALDH1A1ROCK2RPS6KA5RPS6KA4 | |
| SCHEMBL4062930 | 0.84 | ROCK2 (0.48) | EGLN1ROCK2RPS6KA5RPS6KA4PRKACA | |
| SCHEMBL4068267 | 0.84 | ROCK2 (0.48) | EGLN1ROCK2RPS6KA5RPS6KA4PRKACA | |
| SCHEMBL7952597 | 0.81 | EGLN1 (0.62) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL7952982 | 0.81 | EGLN1 (0.62) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL7952980 | 0.81 | EGLN1 (0.62) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL7956801 | 0.79 | EGLN1 (0.57) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL7956796 | 0.79 | EGLN1 (0.57) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL7691064 | 0.79 | SLC2A1 (0.68) | EGLN1ALDH1A1SLC2A1 | |
| SCHEMBL7239347 | 0.79 | ROCK2 (0.55) | ROCK2RPS6KA5RPS6KA4PRKACAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |