Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.78 |
| ▸ | ITGAV | P06756 | 20/20 | 0.78 |
| ▸ | ITGB6 | P18564 | 16/20 | 0.78 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.78 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849800 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| SCHEMBL20140511 | 0.87 | ITGB3 (0.79) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| SCHEMBL20140982 | 0.87 | ITGB3 (0.79) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| SCHEMBL20139504 | 0.87 | ITGB3 (0.79) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| Hydrochloric Acid SCHEMBL5847779 | 0.87 | ITGB3 (0.98) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| Hydrochloric Acid SCHEMBL5847692 | 0.80 | ITGB3 (0.83) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| SCHEMBL20140268 | 0.80 | ITGB3 (0.73) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| SCHEMBL29797431 | 0.80 | ITGB3 (0.73) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| SCHEMBL8335760 | 0.77 | ITGB3 (0.73) | ITGB3ITGAVITGB6ITGA2BITGB8 | |
| SCHEMBL23802056 | 0.77 | ITGB3 (0.81) | ITGB3ITGAVITGB6ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058760-A1 | THIAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |