Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8306452 | 0.91 | CYP11B1 (0.48) | CYP11B1CYP11B2CDC25ACDC25BCDC25C | |
| SCHEMBL5891934 | 0.80 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL5891899 | 0.80 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL8306479 | 0.80 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8190888 | 0.79 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8188315 | 0.79 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL5891885 | 0.79 | CYP11B1 (0.71) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8310145 | 0.79 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL5891408 | 0.79 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8188656 | 0.78 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP19A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891343-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036886-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0891343-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036886-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |