⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938938 | 0.90 | MAPK1 (0.42) | — | |
| SCHEMBL4159314 | 0.87 | MAPK1 (0.48) | — | |
| SCHEMBL8310482 | 0.84 | — | — | |
| SCHEMBL6223853 | 0.81 | ALDH1A1 (0.46) | — | |
| SCHEMBL8309705 | 0.80 | — | — | |
| SCHEMBL25075398 | 0.78 | KDM4E (0.46) | — | |
| SCHEMBL12721326 | 0.77 | TSHR (0.52) | — | |
| SCHEMBL5933722 | 0.77 | MAPK1 (0.43) | — | |
| SCHEMBL5933233 | 0.77 | MAPK1 (0.43) | — | |
| SCHEMBL1796245 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |
| US-5821246-A | USEFUL AS TYROSINE KINASE INHIBITORS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER | ZENECA LIMITED (GB) | 1998-10-13 | — | — | US | disclosed |