Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.71 |
| ▸ | CTSK | P43235 | 11/20 | 0.71 |
| ▸ | CTSB | P07858 | 4/20 | 0.64 |
| ▸ | CTSL | P07711 | 2/20 | 0.64 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.59 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.59 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.59 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860818 | 0.93 | CTSS (0.79) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL30687389 | 0.92 | CTSS (0.63) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL16908125 | 0.92 | CTSS (0.63) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL16908103 | 0.92 | CTSS (0.63) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL3383006 | 0.88 | CTSS (0.77) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16899181 | 0.87 | PSMB8 (0.60) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL16899182 | 0.87 | PSMB8 (0.60) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL16908000 | 0.87 | CTSS (0.64) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL30687361 | 0.87 | CTSS (0.64) | CTSSCTSKCTSBCTSLPSMB1 | |
| SCHEMBL16907991 | 0.86 | CTSS (0.57) | CTSSCTSKCTSBCTSLPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |