SCHEMBL8310362

SCHEMBL8310362

CCOC(=O)c1ccc(OC)c(OCCCl)c1Br

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.42
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41
TUBB1 Q9H4B7 1/20 0.41
MAPT P10636 4/20 0.40
LMNA P02545 3/20 0.40
CDC25B P30305 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8309761 0.85 KMT2A (0.43) MAPTLMNASMN1; SMN2TSHRNPSR1
SCHEMBL1302187 0.79 MAOB (0.46) MAPTLMNASMN1; SMN2GAATDP1
SCHEMBL21828876 0.78 SMN1; SMN2 (0.50) MAPTSMN1; SMN2TSHRNPSR1GAA
SCHEMBL1301130 0.76 HSD17B2 (0.48) DPP4TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL21828912 0.75 SMN1; SMN2 (0.47) MAPTLMNASMN1; SMN2TSHRGAA
SCHEMBL4823776 0.75 MAPT (0.49) DPP4MAPTLMNACDC25BSMN1; SMN2
SCHEMBL8492599 0.75 MAPT (0.52) MAPTSMN1; SMN2TSHRNPSR1GAA
SCHEMBL8491964 0.75 KMT2A (0.44) MAPTSMN1; SMN2TSHRNPSR1GAA
SCHEMBL875062 0.75 KMT2A (0.48) DPP4MAPTLMNACDC25BSMN1; SMN2
SCHEMBL8307840 0.74 MAPT (0.41) MAPTLMNATSHRNPSR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0918056-A1 Herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1999-05-26 EP disclosed