Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613660 | 0.87 | KMT2A (0.59) | KMT2AMEN1PKMPDE4DDPP4 | |
| SCHEMBL3470803 | 0.82 | MEN1 (0.52) | KMT2AMEN1PKMPDE4DDPP4 | |
| SCHEMBL7437362 | 0.79 | LMNA (0.55) | KMT2AMEN1PKMDPP4MAPT | |
| SCHEMBL4823776 | 0.78 | MAPT (0.49) | KMT2AMEN1PKMDPP4MAPT | |
| SCHEMBL27774545 | 0.78 | KMT2A (0.56) | KMT2AMEN1PKMPDE4DMAPT | |
| SCHEMBL7535764 | 0.77 | TSHR (0.47) | KMT2AMEN1PKMDPP4MAPT | |
| SCHEMBL31228795 | 0.77 | TSHR (0.47) | KMT2ADPP4GAATSHRALDH1A1 | |
| SCHEMBL7851443 | 0.77 | MAPT (0.50) | KMT2AMEN1PKMDPP4MAPT | |
| SCHEMBL7688461 | 0.76 | KMT2A (0.65) | KMT2AMEN1MAPTLMNATSHR | |
| SCHEMBL8377258 | 0.76 | TP53 (0.40) | PDE4DMAPTLMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040499-A2 | METABOLIC INHIBITORS | SURFACE LOGIX, INC. (US) | 2012-03-29 | — | — | WO | disclosed |