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SCHEMBL8310370

SCHEMBL8310370

CC(C)(C)OC(=O)CC1C=CC=C(NC(=O)NC2CN(c3ccccc3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)C1=S

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 6/20 0.40
▸ NPY1R P25929 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8310266 0.89 CCKBR (0.42) CCKBRNPY1R
SCHEMBL542390 0.78 CCKBR (0.49) CCKBR
SCHEMBL6176578 0.78 CCKBR (0.43) CCKBRNPY1R
SCHEMBL542264 0.78 CCKBR (0.48) CCKBR
SCHEMBL6176572 0.76 CCKBR (0.50) CCKBRNPY1R
SCHEMBL6179147 0.75 CCKBR (0.47) CCKBRNPY1R
SCHEMBL6180592 0.75 CCKBR (0.46) CCKBRNPY1R
SCHEMBL6180595 0.75 CCKBR (0.46) CCKBRNPY1R
SCHEMBL7661388 0.75 CCKAR (0.47) CCKBR
SCHEMBL7653390 0.75 CCKAR (0.47) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945445-A1 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-09-29 — — EP disclosed