Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.56 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18251698 | 0.90 | ERCC1 (0.50) | ERCC1ERCC4CARM1PRMT6TACR1 | |
| SCHEMBL5025058 | 0.84 | TACR1 (0.50) | ERCC1ERCC4CARM1PRMT6TACR1 | |
| SCHEMBL12864453 | 0.83 | ERCC1 (0.58) | ERCC1ERCC4LMNAALDH1A1MEN1 | |
| SCHEMBL8310068 | 0.81 | MEN1 (0.63) | ERCC1ERCC4CARM1PRMT6LMNA | |
| SCHEMBL12452827 | 0.81 | ERCC1 (0.56) | ERCC1ERCC4CARM1PRMT6LMNA | |
| SCHEMBL20428059 | 0.79 | ERCC1 (0.57) | ERCC1ERCC4CARM1PRMT6TACR1 | |
| SCHEMBL4068730 | 0.79 | TACR1 (0.50) | TACR1P2RX7WDR5ALDH1A1KDM4E | |
| SCHEMBL12131750 | 0.78 | ERCC1 (0.70) | ERCC1ERCC4LMNAMEN1KMT2A | |
| SCHEMBL8310339 | 0.78 | ERCC1 (0.56) | ERCC1ERCC4ALDH1A1L3MBTL1 | |
| SCHEMBL8310378 | 0.77 | TSHR (0.66) | ERCC1ERCC4LMNAPTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |