Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.64 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 7/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671195 | 0.87 | ERCC1 (0.60) | TSHRERCC1ERCC4PTGES | |
| SCHEMBL18251688 | 0.87 | ERCC1 (0.60) | TSHRERCC1ERCC4SMN1; SMN2HRH3 | |
| SCHEMBL18133710 | 0.87 | TSHR (0.62) | TSHRERCC1ERCC4SMN1; SMN2HRH3 | |
| SCHEMBL17977292 | 0.86 | ERCC1 (0.59) | TSHRERCC1ERCC4PTGES | |
| Hydrochloric Acid SCHEMBL18130580 | 0.86 | TSHR (0.60) | TSHRERCC1ERCC4SMN1; SMN2HRH3 | |
| SCHEMBL14368077 | 0.86 | ERCC1 (0.59) | TSHRERCC1ERCC4PTGESLMNA | |
| SCHEMBL18791419 | 0.84 | TSHR (0.68) | TSHRERCC1ERCC4SMN1; SMN2HRH3 | |
| SCHEMBL14782824 | 0.84 | PTGES (0.59) | TSHRERCC1ERCC4PTGESALDH1A1 | |
| SCHEMBL22060011 | 0.84 | NR1H4 (0.59) | TSHRERCC1ERCC4SMN1; SMN2HRH3 | |
| SCHEMBL29463256 | 0.84 | PTGES (0.59) | TSHRERCC1ERCC4PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |