Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200776 | 0.88 | NPC1 (0.60) | NPC1MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9925462 | 0.87 | KDM4E (0.68) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9100540 | 0.84 | PTPN7 (0.63) | KDM4EPTPN7KMT2AMEN1ALDH1A1 | |
| SCHEMBL1312768 | 0.84 | PTPN7 (0.72) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9786970 | 0.80 | MAPT (0.74) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1068092 | 0.77 | MAPT (0.69) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2793970 | 0.75 | MAPT (0.56) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8310667 | 0.75 | PLAU (0.58) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8136104 | 0.75 | MAPT (0.67) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| Methane SCHEMBL28765047 | 0.75 | MAPT (0.67) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217794-B2 | Compounds and methods for treatment of thrombosis | DAIAMED, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |