Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252411 | 0.86 | FFAR1 (0.65) | PTPN7FFAR1PTGDR2ALOX15MMP2 | |
| SCHEMBL2346349 | 0.84 | FFAR1 (0.62) | PTPN7FFAR1PTGDR2ALOX15MMP2 | |
| SCHEMBL4076964 | 0.84 | PTPN7 (0.85) | PTPN7FFAR1ALOX15KDM4EMEN1 | |
| SCHEMBL8310602 | 0.84 | KDM4E (0.55) | PTPN7SLC6A2SLC6A4SLC6A3PORCN | |
| SCHEMBL3190220 | 0.82 | ALOX15 (0.61) | PTPN7FFAR1PTGDR2ALOX15 | |
| SCHEMBL4284626 | 0.81 | MMP2 (0.71) | FFAR1PTGDR2ALOX15MMP2KDM4E | |
| SCHEMBL29367022 | 0.78 | PTPN7 (1.00) | PTPN7FFAR1ALOX15KDM4EMEN1 | |
| SCHEMBL25640 | 0.78 | PTPN7 (1.00) | PTPN7FFAR1ALOX15KDM4EMEN1 | |
| SCHEMBL31453936 | 0.78 | ALOX15 (0.53) | PTPN7FFAR1PTGDR2ALOX15MMP2 | |
| SCHEMBL5867304 | 0.77 | FFAR1 (0.54) | PTPN7FFAR1PTGDR2ALOX15MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481021-A | Phenyl amidines derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0574545-B1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1994-11-30 | — | — | EP | disclosed |
| EP-0574545-A1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. | SEARLE & CO (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015607-A2 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | disclosed |