Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESRRG | P62508 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658326 | 0.81 | KMT2A (0.50) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL8257466 | 0.80 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5436124 | 0.80 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL12124255 | 0.80 | RAB9A (0.77) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL2203250 | 0.80 | HDAC4 (0.63) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL27537637 | 0.79 | HPGD (0.71) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL12124283 | 0.79 | RAB9A (0.75) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL13461888 | 0.78 | F10 (0.55) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL3448527 | 0.78 | KMT2A (0.58) | RAB9ASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL4691317 | 0.77 | F10 (0.54) | RAB9ASMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |