Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | IAPP | P10997 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679305 | 0.95 | HTT (0.55) | HTTCTBP2CNR2PKMHPGD | |
| SCHEMBL15178188 | 0.89 | CTBP2 (0.53) | HTTCTBP2CNR2IAPPPKM | |
| SCHEMBL6225369 | 0.84 | CTBP2 (0.47) | HTTCTBP2PKMGLSNPC1 | |
| SCHEMBL10735937 | 0.83 | CTBP2 (0.50) | HTTCTBP2PKMGLSNPC1 | |
| SCHEMBL7150897 | 0.82 | CTBP2 (0.51) | HTTCTBP2PKMNPC1RAB9A | |
| SCHEMBL31365969 | 0.81 | CTBP2 (0.58) | CTBP2PKMNPC1RAB9ASHBG | |
| SCHEMBL6194349 | 0.81 | CTBP2 (0.58) | CTBP2PKMNPC1RAB9ASHBG | |
| SCHEMBL29233348 | 0.81 | IAPP (0.59) | HTTIAPPALDH1A1CES2CES1 | |
| SCHEMBL1538027 | 0.79 | VNN1 (0.48) | HTTCNR2IAPPRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8183611 | 0.78 | IAPP (0.45) | HTTIAPPALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915867-A1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003498-A1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 1998-01-29 | — | — | WO | disclosed |