SCHEMBL8310776

SCHEMBL8310776

O=C(c1cnoc1C1CC1)c1ccc(Br)c2c1OCCS2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8312009 0.91 DHODH (0.33) DHODH
SCHEMBL8309488 0.87 DHODH (0.33) DHODH
SCHEMBL8306877 0.87 DHODH (0.35) DHODH
SCHEMBL8311110 0.84 ALDH1A1 (0.33) DHODH
SCHEMBL8310666 0.83 PDE2A (0.31) DHODH
SCHEMBL8308304 0.83 DHODH (0.35) DHODH
SCHEMBL8310670 0.83 DHODH (0.33) DHODH
SCHEMBL8307169 0.83 PDE2A (0.33) DHODH
SCHEMBL8307209 0.80 HSD17B10 (0.39) DHODH
SCHEMBL8307248 0.80 ALDH1A1 (0.33) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0918056-A1 Herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1999-05-26 EP disclosed