Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195874 | 1.00 | TSHR (0.42) | TSHRSLC5A2TLR9GBA1TDP1 | |
| SCHEMBL1493181 | 1.00 | TSHR (0.42) | TSHRSLC5A2TLR9GBA1TDP1 | |
| SCHEMBL5195871 | 1.00 | TSHR (0.42) | TSHRSLC5A2TLR9GBA1TDP1 | |
| SCHEMBL31231840 | 0.89 | TLR9 (0.47) | TSHRTLR9GBA1SLC6A2SLC6A4 | |
| SCHEMBL12459457 | 0.86 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL12582923 | 0.86 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL7147747 | 0.86 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL13446904 | 0.84 | SLC5A2 (0.55) | SLC5A2 | |
| SCHEMBL7173273 | 0.83 | TLR9 (0.42) | TSHRSLC5A2TLR9GBA1TDP1 | |
| SCHEMBL12582958 | 0.80 | SLC5A2 (0.44) | SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901480-A4 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0901480-A1 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5847169-A | Process for preparing oxiranemethanamine derivatives | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997042180-A1 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-11-13 | — | — | WO | disclosed |