Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31231840 | 0.85 | TLR9 (0.47) | TLR9SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL5195874 | 0.83 | TSHR (0.42) | TLR9TDP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1493181 | 0.83 | TSHR (0.42) | TLR9TDP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8310780 | 0.83 | TSHR (0.42) | TLR9TDP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5195871 | 0.83 | TSHR (0.42) | TLR9TDP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7173277 | 0.78 | MEN1 (0.44) | TLR9SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL15553027 | 0.77 | TLR9 (0.47) | TLR9TDP1TSHRFASN | |
| SCHEMBL15549575 | 0.77 | TLR9 (0.47) | TLR9TDP1TSHRFASN | |
| SCHEMBL18802162 | 0.77 | TLR9 (0.47) | TLR9TDP1TSHRFASN | |
| SCHEMBL31595612 | 0.75 | TP53 (0.42) | TLR9SLC6A2SLC6A4SLC6A3FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988789-B1 | Reduced pitting microbicide formulation | ROHM & HAAS (US) | 2003-08-27 | — | — | EP | claimed |
| EP-0923564-A4 | PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| EP-0923564-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008829-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |