Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310840 | 0.77 | PPARA (0.42) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL8922764 | 0.74 | PPARG (0.42) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL6372914 | 0.73 | PPARA (0.47) | ACEPPARAPPARGL3MBTL1 | |
| SCHEMBL10268771 | 0.71 | ACE (0.58) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL1741031 | 0.71 | ACE (0.58) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL1357871 | 0.71 | ACE (0.58) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL8311399 | 0.70 | PPARA (0.37) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL5418068 | 0.70 | CYP1A2 (0.55) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL4462979 | 0.69 | PPARG (0.40) | ACEPPARAPPARGCYP2C19 | |
| SCHEMBL723034 | 0.69 | CYP2C19 (0.52) | ACEPPARAPPARGCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724601-A4 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORP (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0724601-A1 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995005398-A1 | S3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |