Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462979 | 0.85 | PPARG (0.40) | PPARAPPARGACECYP2C19CES1 | |
| SCHEMBL8310840 | 0.82 | PPARA (0.42) | PPARAPPARGACECYP2C19PPARD | |
| SCHEMBL8922764 | 0.82 | PPARG (0.42) | PPARAPPARGACECYP2C19CES1 | |
| SCHEMBL8314036 | 0.77 | PPARA (0.36) | PPARAPPARGACECYP2C19CES1 | |
| SCHEMBL8310839 | 0.70 | ACE (0.42) | PPARAPPARGACECYP2C19 | |
| SCHEMBL18270379 | 0.68 | PPARA (0.47) | PPARAPPARGACECYP2C19 | |
| SCHEMBL4983034 | 0.68 | PPARA (0.47) | PPARAPPARGACECYP2C19 | |
| SCHEMBL8314038 | 0.68 | CYP2C19 (0.35) | PPARAPPARGCYP2C19CES1 | |
| SCHEMBL10420286 | 0.68 | MEN1 (0.43) | CYP2C19CES1CPA1 | |
| SCHEMBL10420288 | 0.68 | MEN1 (0.43) | CYP2C19CES1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724601-A4 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORP (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0724601-A1 | S 3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995005398-A1 | S3N CHELATING COMPOUNDS FOR THE RADIOLABELING OF LIGANDS, ANTI-LIGANDS OR OTHER PROTEINS | NEORX CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |