Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31248396 | 0.82 | TACR1 (0.57) | TACR1P2RX7ALDH1A1HPGDMEN1 | |
| SCHEMBL6361162 | 0.82 | NPC1 (0.59) | P2RX7ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL30259909 | 0.82 | NPC1 (0.59) | P2RX7ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL17513342 | 0.81 | TACR1 (0.59) | TACR1P2RX7ALDH1A1HPGDMEN1 | |
| SCHEMBL7932262 | 0.81 | TACR1 (0.55) | TACR1P2RX7ALDH1A1HPGDMEN1 | |
| SCHEMBL1709315 | 0.81 | HPGD (0.70) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL23135792 | 0.80 | P2RX7 (0.52) | TACR1P2RX7ALDH1A1HPGDMEN1 | |
| SCHEMBL4068730 | 0.80 | TACR1 (0.50) | TACR1P2RX7ALDH1A1MEN1KMT2A | |
| SCHEMBL19377955 | 0.80 | MEN1 (0.49) | TACR1P2RX7ALDH1A1HPGDMEN1 | |
| SCHEMBL14672776 | 0.78 | GAA (0.44) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |