Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109175 | 0.81 | MAPT (0.35) | MAPTKDM4EALDH1A1TDP1XIAP | |
| SCHEMBL19736290 | 0.79 | XIAP (0.33) | MAPTKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL19736194 | 0.79 | XIAP (0.33) | MAPTKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL9414018 | 0.78 | — | — | |
| SCHEMBL16754393 | 0.78 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL28380362 | 0.78 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL28381212 | 0.78 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL16238377 | 0.76 | GAA (0.41) | MAPTKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL16238653 | 0.76 | GAA (0.41) | MAPTKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL16238376 | 0.76 | GAA (0.41) | MAPTKDM4EALDH1A1XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590428-B1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AG (DE) | 1999-12-15 | — | — | EP | disclosed |
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0590428-A1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |