Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 3/20 | 0.41 |
| ▸ | FLT1 | P17948 | 3/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308548 | 0.81 | HPGD (0.54) | JUNNFKB1NFKB2RELAKDM4E | |
| SCHEMBL20152022 | 0.80 | JUN (0.48) | JUNNFKB1NFKB2RELAKDM4E | |
| SCHEMBL20460466 | 0.79 | JUN (0.48) | JUNNFKB1NFKB2RELAKMT2A | |
| SCHEMBL936146 | 0.78 | JUN (0.47) | JUNNFKB1NFKB2RELAKMT2A | |
| SCHEMBL8310937 | 0.78 | NPC1 (0.47) | JUNNFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL937874 | 0.77 | JUN (0.46) | JUNNFKB1NFKB2RELA | |
| SCHEMBL8310344 | 0.77 | JUN (0.48) | JUNNFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL20460443 | 0.76 | HPGD (0.49) | JUNNFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL29095024 | 0.75 | KDM4E (0.43) | SMN1; SMN2EGLN1GLAPKMKDM4E | |
| SCHEMBL939217 | 0.75 | JUN (0.44) | JUNNFKB1NFKB2RELAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918769-A1 | SUBSTITUTED PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTI-BACTERIAL AGENTS | AstraZeneca AB (SE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998001446-A1 | SUBSTITUTED PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTI-BACTERIAL AGENTS | ZENECA LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |