Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311661 | 0.88 | RXFP1 (0.58) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8305681 | 0.85 | RXFP1 (0.66) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8311179 | 0.82 | KMT2A (0.47) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8305683 | 0.73 | RXFP1 (0.60) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8311182 | 0.73 | RXFP1 (0.61) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8303958 | 0.72 | ATM (0.58) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8311188 | 0.72 | KMT2A (0.74) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8311517 | 0.72 | RXFP1 (0.58) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8305679 | 0.71 | RXFP1 (0.71) | RXFP1THRBLMNAKMT2AHTT | |
| SCHEMBL8311184 | 0.71 | RXFP1 (0.60) | RXFP1THRBLMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |