Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6064365 | 0.80 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL7049189 | 0.70 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7486869 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5210855 | 0.68 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5207855 | 0.68 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7256774 | 0.67 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL5207098 | 0.66 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7487520 | 0.65 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL5205329 | 0.64 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5208892 | 0.64 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904269-A1 | 3,4-DIARYL-2-HYDROXY-2,5-DIHYDROFURANS AS PRODRUGS TO COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1999-03-31 | — | — | EP | disclosed |
| WO-1997016435-A1 | 3,4-DIARYL-2-HYDROXY-2,5-DIHYDROFURANS AS PRODRUGS TO COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-05-09 | — | — | WO | disclosed |