Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14184314 | 0.86 | TMIGD3 (0.62) | TMIGD3ADORA1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14303513 | 0.84 | ALDH1A1 (0.62) | TMIGD3ADORA1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2843704 | 0.82 | KDM4E (0.50) | TMIGD3ADORA1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18351094 | 0.77 | MAPK1 (0.58) | TMIGD3ADORA1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13005006 | 0.76 | BRD4 (0.78) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL14875649 | 0.74 | TYMS (0.47) | TMIGD3ADORA1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL16298727 | 0.74 | MAPK1 (1.00) | TMIGD3ADORA1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8989109 | 0.73 | TNKS2 (0.57) | KDM4ESMN1; SMN2KMT2ARAB9ATNKS | |
| SCHEMBL3491840 | 0.72 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL2843024 | 0.72 | TMIGD3 (0.46) | TMIGD3ADORA1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065391-A1 | 4-AMINOTHIENO[2,3-d]PYRIMIDINE-6-CARBONITRILE DERIVATIVES AS PDE7 INHIBITORS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-08-05 | — | — | WO | disclosed |