Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798646 | 0.93 | PDE4B (0.44) | PDE4BPDE4DTP53MAPTRXFP1 | |
| SCHEMBL6796619 | 0.86 | PDE4B (0.40) | PDE4BPDE4DTP53MAPTRXFP1 | |
| SCHEMBL6796219 | 0.85 | EGFR (0.44) | PDE4BPDE4DTP53MAPTMEN1 | |
| SCHEMBL6797424 | 0.84 | PDE4B (0.46) | PDE4BPDE4DTP53RXFP1 | |
| Hydrochloric Acid SCHEMBL6794144 | 0.84 | EGFR (0.43) | PDE4BPDE4DTP53MAPTMEN1 | |
| SCHEMBL6796610 | 0.84 | WDR5 (0.41) | PDE4BPDE4DTP53MAPTRXFP1 | |
| SCHEMBL6798698 | 0.83 | RXFP1 (0.42) | PDE4BPDE4DTP53RXFP1 | |
| SCHEMBL8311520 | 0.82 | PDE4B (0.43) | PDE4BPDE4DTP53MAPTRXFP1 | |
| SCHEMBL6799861 | 0.82 | EGFR (0.40) | PDE4BPDE4DTP53MAPTRXFP1 | |
| Sulfuric Acid SCHEMBL7827766 | 0.82 | MEN1 (0.42) | PDE4BPDE4DMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920867-A1 | Pyrido[2,3-a]pyrazine derivatives as PDE-IV and TNF inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-06-09 | — | — | EP | disclosed |