Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310974 | 0.90 | MEN1 (0.65) | MEN1KMT2APOLBMAPTTP53 | |
| SCHEMBL8303990 | 0.88 | KDM4E (0.63) | MEN1KMT2APOLBPKMMAPT | |
| SCHEMBL8307716 | 0.88 | KDM4E (0.65) | MEN1KMT2APOLBPKMMAPT | |
| SCHEMBL8307118 | 0.88 | KDM4E (0.67) | MEN1KMT2APOLBPKMMAPT | |
| SCHEMBL8312056 | 0.88 | KDM4E (0.67) | MEN1KMT2APOLBPKMMAPT | |
| SCHEMBL8307121 | 0.88 | KDM4E (0.67) | MEN1KMT2APOLBPKMMAPT | |
| SCHEMBL8304126 | 0.86 | ALDH1A1 (0.67) | MEN1KMT2AMAPTTP53USP2 | |
| SCHEMBL8306930 | 0.84 | POLB (0.66) | MEN1KMT2APOLBPKMMAPT | |
| SCHEMBL8308901 | 0.83 | KDM4E (0.68) | MEN1KMT2APOLBTP53USP2 | |
| SCHEMBL8307719 | 0.83 | POLB (0.58) | MEN1KMT2APOLBPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |