Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 16/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 15/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863820 | 0.88 | DPP4 (0.64) | DPP4DPP8DPP7 | |
| SCHEMBL14159518 | 0.85 | DPP4 (0.60) | DPP4DPP8DPP7 | |
| SCHEMBL4866220 | 0.82 | DPP4 (0.60) | DPP4DPP8DPP7 | |
| SCHEMBL8312244 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL1846959 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL21067640 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL1394444 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5043367 | 0.75 | DPP4 (0.98) | DPP4DPP8DPP7 | |
| SCHEMBL10195795 | 0.74 | DPP4 (0.74) | DPP4DPP8DPP7 | |
| SCHEMBL21853403 | 0.74 | DPP4 (0.74) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388019-B2 | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. (US) | 2008-06-17 | — | — | US | disclosed |
| US-7388019-B2 | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. (US) | 2008-06-17 | — | — | US | disclosed |
| WO-2004069162-A2 | 3-AMINO-4-PHENYLBUTANOIC ACID DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO., INC. (US) | 2004-08-19 | — | — | WO | disclosed |