SCHEMBL21067640

SCHEMBL21067640

C[C@@H]1C(=O)NCCCN1C(=O)CC(N)Cc1cc(F)c(F)cc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 19/20 1.00
DPP8 Q6V1X1 14/20 1.00
DPP7 Q9UHL4 11/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1394444 1.00 DPP4 (1.00) DPP4DPP8DPP7
SCHEMBL1846959 1.00 DPP4 (1.00) DPP4DPP8DPP7
Hydrochloric Acid SCHEMBL5043367 0.99 DPP4 (0.98) DPP4DPP8DPP7
SCHEMBL27827304 0.85 DPP4 (0.74) DPP4DPP8DPP7
SCHEMBL388929 0.84 DPP4 (1.00) DPP4DPP8DPP7
SCHEMBL21067975 0.84 DPP4 (1.00) DPP4DPP8DPP7
SCHEMBL4761339 0.83 DPP4 (1.00) DPP4DPP8DPP7
SCHEMBL4708250 0.83 DPP4 (1.00) DPP4DPP8DPP7
SCHEMBL4761344 0.83 DPP4 (1.00) DPP4DPP8DPP7
Hydrochloric Acid SCHEMBL4160735 0.83 DPP4 (0.98) DPP4DPP8DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
EP-2906542-B1 SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS MERCK SHARP & DOHME (US) 2019-08-07 EP disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed