Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312648 | 0.99 | KDM4E (0.58) | KDM4ETSHRALDH1A1MAPTKMT2A | |
| SCHEMBL8311813 | 0.99 | KDM4E (0.58) | KDM4ETSHRALDH1A1MAPTKMT2A | |
| SCHEMBL8312512 | 0.96 | ALDH1A1 (0.56) | KDM4ETSHRALDH1A1MAPTKMT2A | |
| SCHEMBL8305957 | 0.90 | CA12 (0.53) | KDM4ETSHRALDH1A1MAPTKMT2A | |
| SCHEMBL8312223 | 0.83 | BACE1 (0.71) | KDM4EALDH1A1MAPTKMT2ATP53 | |
| SCHEMBL8308428 | 0.82 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL17308418 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL8312510 | 0.81 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL8305716 | 0.81 | KDM4E (0.62) | KDM4ETSHRALDH1A1MAPTKMT2A | |
| SCHEMBL8305815 | 0.81 | KDM4E (0.62) | KDM4ETSHRALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |