Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308039 | 0.90 | EGFR (0.57) | EGFRGRM1 | |
| SCHEMBL8308420 | 0.90 | EGFR (0.57) | EGFRGRM1 | |
| SCHEMBL8312424 | 0.88 | EGFR (0.56) | EGFRGRM1IRAK4 | |
| SCHEMBL8308696 | 0.87 | EGFR (0.58) | EGFRGRM1 | |
| SCHEMBL8311428 | 0.85 | EGFR (0.56) | EGFRGRM1 | |
| SCHEMBL8306177 | 0.78 | GRM1 (0.55) | EGFRGRM1 | |
| SCHEMBL6363717 | 0.73 | CD38 (0.56) | CD38IRAK4 | |
| SCHEMBL8308249 | 0.73 | CD38 (0.56) | CD38IRAK4 | |
| SCHEMBL6363714 | 0.73 | CD38 (0.56) | CD38IRAK4 | |
| SCHEMBL8306375 | 0.73 | GRM1 (0.49) | GRM1CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016925-A1 | AZAQUINAZOLINE DERIVATIVES | PFIZER LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |