Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204704 | 0.95 | ALDH1A1 (0.62) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3696420 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8373505 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8205008 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8549614 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8373486 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8315263 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL3113016 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8374769 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL8192951 | 0.89 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597102-B1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION | YAMANOUCHI PHARMA CO LTD (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5508296-A | HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0597102-A1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |