SCHEMBL8312541

SCHEMBL8312541

O=CCCNCCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15028890 0.96 HIF1A (0.44)
SCHEMBL29349589 0.89 HIF1A (0.47)
SCHEMBL13625477 0.87 HIF1A (0.53)
SCHEMBL6357543 0.84
SCHEMBL7697738 0.84
SCHEMBL2387372 0.84
SCHEMBL11698057 0.84
SCHEMBL4454530 0.84
SCHEMBL24863800 0.82 ALDH1A1 (0.36)
SCHEMBL12948527 0.80 HIF1A (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125007-B9 CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR UNIV CALIFORNIA (US) 2014-04-16 EP disclosed
EP-2125007-B1 CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR UNIV CALIFORNIA (US) 2014-01-08 EP disclosed
WO-2009110523-A2 DENDRIMER PARTICLE, MRI CONTRAST MEDIUM, AND METHOD OF MANUFACTURING A DENDRIMER PARTICLE KYOTO UNIVERSITY (JP) 2009-09-11 WO disclosed
EP-0946517-A1 N-(IMIDAZOLYLBUTYL) BENZENESULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION SYNTHELABO (FR) 1999-10-06 EP disclosed
WO-1998022443-A1 N-(IMIDAZOLYLBUTYL) BENZENESULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION SYNTHELABO (FR) 1998-05-28 WO disclosed
CN-1114834-A antidiabetic agent OTSUKA PHARMA CO LTD (JP) 1996-01-10 CN disclosed
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 EP disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed
US-4202816-A ENOL-PIPERIDINE METAL COMPLEXES CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed