Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312604 | 0.85 | EGFR (0.61) | EGFRMEN1KMT2A | |
| SCHEMBL8306177 | 0.84 | GRM1 (0.55) | EGFRGRM1 | |
| SCHEMBL8313080 | 0.83 | EGFR (0.61) | EGFRMEN1 | |
| SCHEMBL8306375 | 0.82 | GRM1 (0.49) | GRM1 | |
| SCHEMBL8308039 | 0.82 | EGFR (0.57) | EGFRGRM1 | |
| SCHEMBL8308420 | 0.82 | EGFR (0.57) | EGFRGRM1 | |
| SCHEMBL8312990 | 0.81 | MEN1 (0.44) | MEN1KMT2AGRM1 | |
| SCHEMBL8308696 | 0.81 | EGFR (0.58) | EGFRGRM1 | |
| SCHEMBL6369264 | 0.77 | GRM1 (0.45) | GRM1 | |
| SCHEMBL6363927 | 0.75 | AURKA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016925-A1 | AZAQUINAZOLINE DERIVATIVES | PFIZER LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |