Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 5/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314306 | 1.00 | PARP15 (0.54) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL3718600 | 1.00 | PARP15 (0.54) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL22820830 | 0.95 | PARP15 (0.50) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL6686905 | 0.94 | PARP15 (0.58) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL1299143 | 0.93 | HPGD (0.58) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL1299517 | 0.92 | HPGD (0.61) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL1299658 | 0.91 | HPGD (0.59) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL10906512 | 0.91 | HPGD (0.59) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL3067625 | 0.90 | PARP15 (0.54) | PARP15PARP10PARP2HPGDALDH1A1 | |
| SCHEMBL28371333 | 0.88 | ALDH1A1 (0.50) | PARP15PARP10PARP2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597102-B1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF AND HYPOGLYCEMIC COMPOSITION | YAMANOUCHI PHARMA CO LTD (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5508296-A | HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0597102-A1 | NOVEL BISHETEROCYCLIC DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |