Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EPOR | P19235 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17369155 | 0.98 | TPSAB1 (0.47) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL23760082 | 0.94 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL14744316 | 0.89 | TPSAB1 (0.43) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL23760112 | 0.87 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL17369164 | 0.87 | SYK (0.46) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL17369165 | 0.86 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL11007681 | 0.86 | FOLH1 (0.43) | TPSAB1TPSD1TPSG1L3MBTL1SYK | |
| SCHEMBL7785339 | 0.85 | TPSAB1 (0.47) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL7785865 | 0.84 | TPSAB1 (0.46) | TPSAB1TPSD1TPSG1L3MBTL1MAPT | |
| SCHEMBL5970440 | 0.84 | TPSAB1 (0.44) | TPSAB1TPSD1TPSG1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072047-A1 | INDOLES, BENZIMIDAZOLES OR NAPHHIMIDAZOLES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |